What is the Thioacetic acid?

Thioacetic acid is clear,yellow liquid with a strong, unpleasant odor, while it's Molecular Formula is C2H4OS. clear,yellow liquid with a strong, unpleasant odor Chemical reagent, lachrymator.

What is the CAS number for Thioacetic acid?

The CAS number of Thioacetic acid is 507-09-5.

What is Thioacetic acid (507-09-5) used for?

Thioacetic acid, also known as acetyl mercaptan or ethanethioic acid, is a sulfur-containing organic compound used in various synthetic applications, including the enantio- and diastereoselective addition to nitroalkenes for chiral 1,2-aminothiol synthesis and the conversion of L-β-chloroalanine peptides to L-cysteine peptides. It serves as a key reagent in organic transformations, demonstrating versatility in nucleophilic displacement reactions and catalytic processes. Its role in constructing cyclic thiophosphate moieties further highlights its utility in medicinal chemistry, particularly in synthesizing biologically active analogs like 3-O-thia-cPAs.InChI:InChI=1/C2H4OS/c1-2(3)4/h1H3,(H,3,4)

What is the Thioacetic acid?

Thioacetic acid is clear,yellow liquid with a strong, unpleasant odor, while it's Molecular Formula is C2H4OS. clear,yellow liquid with a strong, unpleasant odor Chemical reagent, lachrymator.

What is the CAS number for Thioacetic acid?

The CAS number of Thioacetic acid is 507-09-5.

What is Thioacetic acid (507-09-5) used for?

Thioacetic acid, also known as acetyl mercaptan or ethanethioic acid, is a sulfur-containing organic compound used in various synthetic applications, including the enantio- and diastereoselective addition to nitroalkenes for chiral 1,2-aminothiol synthesis and the conversion of L-β-chloroalanine peptides to L-cysteine peptides. It serves as a key reagent in organic transformations, demonstrating versatility in nucleophilic displacement reactions and catalytic processes. Its role in constructing cyclic thiophosphate moieties further highlights its utility in medicinal chemistry, particularly in synthesizing biologically active analogs like 3-O-thia-cPAs.InChI:InChI=1/C2H4OS/c1-2(3)4/h1H3,(H,3,4)

Detailed introduction

Chemical plants supply high-quality Thiolacetic acid 507-09-5 in bulk

Molecular Formula:C2H4OS
Molecular Weight:76.1192
Appearance/Colour:clear,yellow liquid with a strong, unpleasant odor
Vapor Pressure:50.4mmHg at 25°C
Melting Point:-17 °C
Refractive Index:n20/D 1.465(lit.)
Boiling Point:93 °C at 760 mmHg
PKA:3.33(at 25℃)
Flash Point:11.1 °C
PSA：55.87000
Density:1.046 g/cm³
LogP:0.46270

Thioacetic acid(Cas 507-09-5) Usage

Chemical properties	Thioacetic acid is acid containing thiol group, it is also known as thioacetate, thiol acetic acid, acetic acid. It is yellow fuming liquid with unpleasant and pungent odor, chemical property is active, reactivity is very strong, it can prapare mercaptan by reaction with unsaturated aliphatic hydrocarbon and alcohol. CH3COSH + CH2 = CHCH3 → CH3CH2CH2SH CH3COSH + CH3CH2OH → CH3CH2SH Reaction with ethylene oxide can prepare acetylthio ethanol. CH3COSH + (CH2) 2O → CH3COSCH2CH2OH Four methods of laboratory prepared thioacetic acid: 1, acetic acid and phosphorus pentasulfide at 91℃ react, vacuum distillation is further refined and product can obtain. 5CH3COOH + P2S5 → CH3COSHC2H4OS + P2O5 2, chloride and hydrogen sulfide react, after dilute lye neutralizes and distillation refines. It can be obtained. 3, the reaction of acetic anhydride with hydrogen sulfide, thioacetic acid can be obtained, while byproduct of acetic acid can get. 4, the reaction of ketene with hydrogen sulfide can directly obtain. Uses: In laboratory, it can instead of hydrogen sulfide, it can be used verification of cobalt and lead, determination of molybdenum, sulfur synthetic aldehydes and ketones sulfur, histochemical determination of esterase, it can be used as tear gas and so on.
Production methods	It can be obtained by thermal distillation of ice aldehyde acid with five-thiodipropionic phosphorus. Finely powdered phosphorus pentasulfide is added into glacial acetic acid. When heated to 91℃, it start distilles thioacetic acid, it need to prevent bumping during heating, distillation temperature must not exceed 100 ℃. Distillate distilles once again can derive product.
Hazards & Safety Information	Category: corrosive materials Toxicity grading: highly toxic Acute intraperitoneal toxicity-mouse LD50: 75 mg/kg Flammability Combustible hazardous characteristics: it is combustible, easy to decompose into acetic acid and toxic hydrogen sulfide gas Storage characteristics: Treasury ventilation low-temperature drying; and it should be stored separately with oxidants, alkali. Extinguishant: sand, foam, water spray, carbon dioxide.
Definition	ChEBI: A thioacetic acid that is acetic acid in which the oxygen atom of the hydroxy group has been replaced by a sulfur atom.
General Description	A clear,yellow liquid with a strong, unpleasant odor. May be toxic by ingestion, inhalation and skin absorption. Irritating to skin and eyes. Flash point near 50°F. Used to make other chemicals.
Air & Water Reactions	Highly flammable. Water soluble.
Reactivity Profile	Thioacetic acid is a thio organic acid. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid.
Hazard	Toxic by ingestion and inhalation; strong irritant to eyes and skin.
Health Hazard	May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard	HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility	Highlyflammable
Safety Profile	Poison by intraperitoneal route. A very dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of SOx. See also SULFIDES and MERCAPTANS.