

Available forms:Light yellow to yellow-brownish powder
pd_proNo:539316-47a7a8ce-d482-4788-8682-89aa5c4076ca
pd_productuse:
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Preparation |
synthesis of acetylpyrazine: By the ester condensation of EtO2 C-pyrazine; by dehydrating pyrazynamide with POCI3 and then reacting the resulting 2-cyano-pyrazine with methyl magnesium bromide. |
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Definition |
ChEBI: 2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines. |
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Application |
Acetylpyrazine has been widely used as an intermediate in the organic synthesis of various heterocyclic derivatives and in coupling reactions, alkylation reactions, and sensitizer ligands because of its good biological and reactive activities. For example, it is a significant reaction intermediate for producing drugs for treating malaria, epilepsy, and Parkinson's disease. |
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Aroma threshold values |
Detection at 62 ppb |
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Taste threshold values |
Taste characteristics at 10 ppm: roasted, nutty, bready, yeasty with popcorn, corn chip nuance |
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General Description |
2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust. |
InChI:InChI=1/C6H8N2O/c1-6(9)8-4-2-7-3-5-8/h2-5,7H,1H3
The synthesis of a series of novel thios...
The generation of pyrazines in a binary ...
Because their site-selective C-H functio...
The invention relates to the field of ch...
An efficient and mild protocol has been ...
L-serin
L-lysine
D-glucose
1,4-pyrazine
2-Methylpyrazine
2,5-dimethyl-pyrazine
2,3-dimethylpyrazine
acetylpyrazine
2-ethyl-3,6-dimethylpyrazine
2,6-dimethylpyrazine
2,3,5-trimethylpyrazine
2-ethyl-6-methylpyrazine
2-ethyl-5-methypyrazine
| Conditions | Yield |
|---|---|
|
In
water;
at 130 ℃;
for 2h;
pH=8;
|
L-lysine
D-glucose
1,4-pyrazine
2-Methylpyrazine
2,5-dimethyl-pyrazine
2,3-dimethylpyrazine
acetylpyrazine
2-ethyl-3,6-dimethylpyrazine
2,6-dimethylpyrazine
2,3,5-trimethylpyrazine
2-ethyl-3,5-dimethylpyrazine
2-ethyl-5-methypyrazine
| Conditions | Yield |
|---|---|
|
In
water;
at 130 ℃;
for 2h;
pH=8;
|
2-pyrazine carbonitrile
methylmagnesium bromide
1,4-pyrazine
acetaldehyde
(E)-3-(3-Hydroxy-4-methoxy-phenyl)-1-pyrazin-2-yl-propenone
(E)-3-(3-Ethoxy-4-hydroxy-phenyl)-1-pyrazin-2-yl-propenone
(E)-3-(3-Ethoxy-2-hydroxy-phenyl)-1-pyrazin-2-yl-propenone
(E)-3-(4-Chloro-phenyl)-1-pyrazin-2-yl-propenone
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